CBS
Comparative Bioinformatics Services
Comparative bioinformatics analysis is the cornerstone of in silico-based approaches to understanding biological systems and processes across species, in order to identify genes of interest. There are a number of critical issues common to most bioinformatics strategies for comparative analysis and in this proposal we examine these with a focus on the utilization of the available genome sequences for analyzing the differences and similarities. In this bioinformatics core facility project, our Comparative Bioinformatics team of the Advanced Bioinformatics Core (ABC) will highlight the establishment of an integrated comparative bioinformatics infrastructure for genome annotation/ re-annotation and comparative analysis. The mission of this project is two-fold. First is to support the current and future comparative bioinformatics needs for biomedical and biotechnological applications, and Second is to thoroughly explore the rules behind the genomic sequences. This will not only advance the genomics research in Taiwan, but will also increase Taiwan’s competitiveness in genome-based biomedical and biotechnology industry.
We will provide a solid solution that combines the computational methods and leading-edge information technology into a solid bioinformatics approach. All the services provided will be closely linked with the statistical ability of our Genomic Statistics team, the comprehensive gene expression (transcriptomics and proteomics) analysis for re-usable modules will also be inferred from our Functional Genomics team, and all these supports will be structured on the common informatics platform provided by our Bioinformatics Service Integration and Deployment Infrastructure team. The goal for the Comparative Bioinformatics team is to support both biomedical research and public health. This provided core resource will accelerate scientific progress on understanding, detecting, diagnosing and treating diseases.