臨床計畫審查管理系統(PTMS)教育訓練
- 參加對象: 辦公室人員
- 課程目標: 熟悉如何應用PTMS控管計畫審核作業
- 課程時間: 98年12月25日, PM 2:00~5:00
- 上課地點: 陽明大學圖資大樓517教室
- 報名網址: http://ymadm1.ym.edu.tw/activity/content.asp?actno=412
Add comment December 15th, 2009
Posts filed under 'tools'
LFGO
LFGO - Liver Fibrosis Genes Online
Global gene expression profiling of dimethylnitrosamine-induced liver fibrosis: From pathological and biochemical data to microarray analysis
During the 6-week time course, histopathological, biochemical, and quantitative RT-PCR analyses confirmed the incidence of necroinflammatory and hepatic fibrosis in this established rat model system. Using the Affymetrix microarray chip, 256 differentially expressed genes were identified from the liver injury samples. Hierarchical clustering of gene expression using a gene ontology database allowed the identification of several stage-specific characters and functionally related clusters that encode proteins related to metabolism, cell growth/maintenance, and response to external challenge. Among these genes, we classified 44 potential necroinflammatory-related genes and 62 potential fibrosis-related markers or drug targets based on histopathological scores. We also compared the results with other data on well-known markers and various other microarray datasets that are available.
Add comment May 16th, 2008